RBPJ and neoplasm: We found that the specific tumor cell lysis ability of the T-cells from the RBP-J-/- SPDC-vaccinated mice were significantly lower than that of the T-cells from the control SPDC-vaccinated mice (Fig. 6I), and that the RBP-J-/- SPDC-vaccinated mice possessed smaller draining lymph nodes and spleens as compared with the controls (data not shown).