SELP and viral infectious disease: Our results showing that platelets derived from JUNV-infected cultures had less P-selectin expression upon thrombin stimulation together with the observation that type I IFN-treated megakaryocytes have almost no dense or alpha granules strongly support the hypothesis that megakaryocyte exposure to type I IFN driven by viral infection of bone marrow cells results not only in a reduced number of platelets but also in the generation of dysfunctional platelets.