CD4 and HIV infectious disease: We also examined factors associated with changes in BMI before use of antiretroviral agents among patients diagnosed in the HAART era and found higher time-updated CD4 count (estimate 0.25, p = 0.05), lower time-updated HIV-RNA level (HIV-RNA<1000 copies/mL vs. ≥100000 copies/mL, estimate 0.58, p = 0.01) and longer duration of HIV infection (estimate 0.26, p<0.001) remained associated with greater weight gain (data not shown).