INS and Hypoglycemia: • Rapid acting insulin analogs such as insulin aspart and lispro are safe during gestation, lead to a better control of postprandial levels of glycemia and lower frequency of hypoglycemia. NPH human insulin is still the first choice among those intermediate acting insulins. There are some studies and short communications with the use of long acting insulin analogs detemir and glargine, but more consistent studies are warranted.