SLCO1B3 and cancer: Moreover, Monks at el., following observations that OATP1B3 mRNA is up-regulated in non-small cell lung cancer, transfected HeLa cervical cancer cells with the drug transporters OATP1B1 and OATP1B3 to create in vitro models in which MCs could gain intracellular access and test the activity of MCs against OATP-expressing cancer cells.