Breast cancer (BRCA) proteins and their associated molecules (e.g., Fanconi anemia proteins, Ataxia telangiectasia mutated- Ras-associated diabetes (ATM- RAD complex) work in a network of connected biological complexes that encompass virtually all aspects of the cellular response to DNA damage during the S and G2 phases of the cell cycle.[30] Cells lacking these proteins fail to correct endogenous DNA damage during or after DNA synthesis. This evidence concerns the gene ATM and anemia (phenotype).