CNTN3 and melanoma: A wide range of proteins that control the metastatic character of various tumor cells, including melanoma cells, such as adhesion molecules, growth factors, growth factor receptors and various proteases, are synthesized as inactive precursor proteins that are converted to their bioactive forms directly or indirectly by one or more of the 7 known subtilisin/kexin-like proprotein convertase (PCs) family members.