The association of neurological outcome (CPC 1 to 2 vs. 3 to 5), NSE serum levels and MTH was adjusted for confounders using a logistic regression model including gender, age, APACHE II-score, epinephrine dosage, bystander CPR, time to ROSC, location of cardiac arrest and initial heart rhythm as independent variables. Here, ENO2 is linked to cardiac arrest.