UGT1A1 and Gilbert syndrome: Homozygosity for the promoter 7(TA) repeat in the UDP glucuronosyltransferase 1 family, polypeptide A cluster (UGT1A) gene promoter has been associated with unconjugated hyperbilirubinaemia and Gilbert syndrome.98,99 The normal UGT1A promoter contains an A(TA)nTAA nucleotide-sequence motif with 6 (TA) dinucleotide repeats.