GSTM1 and Schnyder corneal dystrophy: It seems at least that all hematologists agree that they can definitely define the very mild or the “asymptomatic” patients as an obvious phenotype.22–24 Different authors have reported SCD as an inflammatory disease with endothelium involvement.25 Other studies have implicated the NO bio-availability, associated with the scavenging of NO by cell free Hb (product of hemolysis), in the vascular patho-biology of SCD.5