DVL3 and non-small cell lung carcinoma: For example, wingless-related MMTV integration site 1 (WNT1) and wingless-related MMTV integration site 2 (WNT2) are overexpressed in non-small cell lung cancer (NSCLC) (He, B et al. 2004; You et al. 2004); loss of wingless-related MMTV integration site family, member 7A (WNT7A) contributes to the progression of lung cancer through its inability to induce E-cadherin (Ohira et al. 2003); and DVL3 is reported to be overexpressed in NSCLC (Uematsu et al. 2003).