CDH1 and colitis: In this model, colitis was associated with a more than 10-fold increase in the frequency of E-cadherin+ DCs in the colon and MLN compared to unreconstituted Rag2−/− control mice (Figures 1B and 1C), and a more than 3-fold increase in the frequency of E-cadherin+ DCs compared to WT mice (Figure S2A).