In this series of nodular melanomas, location on the trunk compared with other locations had significant prognostic impact in univariate (p < 0.001) and multivariate analyses (HR = 2.6, p = 0.002, if added to the model shown in Table 5), but it did not influence the impact of mitotic count or Ki-67 expression. This evidence concerns the gene MKI67 and nodular malignant melanoma.