Most recently, experimental evidence indicates that AEBP1 mediates LPS-induced foam cell formation by virtue of its ability to directly suppress peroxisome proliferator-activated receptor γ1  (PPARγ1) and liver X receptor α (LXRα) activity in macrophages, suggesting that AEBP1 may play a critical regulatory role in bacterial infection-induced atherosclerosis [267]. Here, AEBP1 is linked to bacterial infectious disease.