CHIA and asthma: They stated that: (1) = the chitinase activity in broncho-alveolar lavage fluids matched that of chitotriosidase but not that of AMCase; (2) = AMCase transcripts in macrophages were consistent with an isoform lacking enzymatic activity; (3) = the chitinase activity in lavage fluids tended to be lower than normal in asthmatic subjects, but was increased 7-fold in habitual smokers; and (4) = chitinase activity did not increase in subjects with asthma and in fact tends to be decreased.