The extent of cerebral infarction was 38 ± 4% of the right, ischemic hemisphere in the remaining animals of the delayed rt-PA group, 22 ± 3% in the control group, 17 ± 3% in the early G-CSF group, 14 ± 3% in com group, and 11 ± 3% in the early thrombolysis group. This evidence concerns the gene CSF3 and brain infarction.