HCV PCR and anti-HCV positive), dengue 33/189 (17.5% or 8.4% of all 392 patients) (NS1 antigen positive and/or anti-dengue IgM/IgG positive), rickettsioses 28/382 (7.3%) (IgM/IgG positive), leptospirosis 26/385 (6.8%) (MAT positive), hepatitis E 6/378 (1.6%. The gene discussed is CD40LG; the disease is leptospirosis.