Considering those with and without leptospirosis, the median (range) AST was lower in those with this disease [85 (25–309) IU/l] than in those without [108 (2–1679) IU/l] (P = 0.01), median (range) ALT was lower in those with [15 (4–164) IU/l] than in those without [31 (2–1305) IU/l] (P = 0.003), the bilirubin:AST ratio was higher in those with [1.163 (0.018-9.095)] than in those without [0.513 (0.027–26.41] (P = 0.004) and the bilirubin:ALT ratio was higher in those with [3.433 (0.171–38.048)] than in those without leptospirosis [1.659 (0.067–66.58)] (P = 0.002). Here, GPT is linked to leptospirosis.