To investigate whether or not the abnormal expression of Bmi-1 is involved in the pathogenesis of ovarian carcinoma, in the present study, the protein expression of Bmi-1 was examined firstly by IHC in normal ovaries, benign and borderline epithelial ovarian tumors, and malignant epithelial cancers. Here, BMI1 is linked to borderline epithelial tumor of ovary.