BACE1 and Alzheimer disease: Using transiently transfected murine neuronal N2acells in culture, in parallel to a mouse model of AD, we were able todemonstrate a role for two miRNAs (miR-298 and miR-328) in the regulationof ß-amyloid (Aß) precursor protein (APP)-converting enzyme (BACE)messenger RNA (mRNA) translation, thereby providing key insights into themolecular basis underlying BACE deregulation in AD.