FOS and neoplasm: In particular, the FOS protein is induced by CC3 in HepG2 but not in U373 (Figure 4B); nucleoredoxin is downregulated by CC3 in three tumor cell lines but not in U373 (Figure 6D); vimentin, whose RNA is upregulated 300 fold in U373cc3 cells (Additional File 2) is practically unchanged at the protein level, but is strongly induced in N417 cells (data not shown).