SLC22A5 and systemic lupus erythematosus: Table 1 summarizes our most confident cis results ordered by RTC Score. We detect SNP-gene combinations passing the 0.9 threshold for 28 intervals out of the 130, twice as many than expected by chance (13 expected top 10% scoring intervals under the uniform distribution). Our method confirms prior results in the literature suggestive of disease effects mediated through expression (ORMDL3 for asthma risk [13], C8orf13 locus for lupus risk [20], SLC22A5 for Crohn's disease [12],[21]).