CD8A and respiratory tract infectious disorder: Further, by quantitative FACS analysis and intracellular staining for IFN-γ, equivalent numbers of virus-specific CD8+ T cells were found in lung, mediastinal lymph nodes and spleens of influenza virus-infected DG/Lck-cre and DGf/f mice mirroring the normal migration and effector function of these cells following respiratory infection [24].