MIF and keratitis: Since MIF regulates the pro-inflammatory responses to LPS challenge in vitro as well as in several in vivo models, we examined how MIF might modulate the molecular responses to P. aeruginosa induced keratitis by measuring local cytokine production based on prior findings as to which mediators are regulated by MIF and a small-scale microarray analysis we performed (data not shown) on infected corneas from WT and MIF KO mice to suggest which cytokines might be candidates for a more thorough investigation.