As shown in Figure 1a, OAZ gene were highly expressed in peripheral blood samples from SLE patients as compared to those from normal controls (0.79 ± 0.13 vs 0.001 ± 0.109, P < 0.0001) and RA patients (0.79 ± 0.13 vs -0.04 ± 0.22, P < 0.01), while there was no difference between those from normal controls and RA patients (P > 0.05). This evidence concerns the gene ZNF423 and systemic lupus erythematosus.