CH tissues expressed the highest levels of BI-1 mRNA (950.81 ± 348.6), significant higher than in PHCC (543.1 ± 345.4; P < 0.0001) or HCC (365.92 ± 185.52; P < 0.0001) tissues (Figure 1A). The gene discussed is TMBIM6; the disease is hepatocellular carcinoma.