Six kallikreins, KLK4, KLK5, KLK6, KLK7, KLK10, and KLK15 (Kim et al, 2001; Kyriakopoulou et al, 2003; Shvartsman et al, 2003; Yousef et al, 2003c; Kountourakis et al, 2008), are markers of poor prognosis in ovarian cancer. The gene discussed is KLK4; the disease is ovarian cancer.