IL12B and cerebral malaria: Given the biological relevance of IL12 in malarial anaemia and the genetic linkage of IL12B in malaria infection and severe disease (cerebral malaria), the potential associations of differences in genes encoding two human IL12 subunits, IL12A and IL12B, and receptors, IL12RB1 and IL12RB2, in the risk of developing SMA has been investigated by retrospectively genotyping samples collected from an infant cohort study, Asembo Bay Cohort Project (ABCP) [24].