Examples of these novel drugs include imatinib (Gleevec), trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva), cetuximab (Erbitux) and panitumumab (Vectibix), and sunitinib (Sutent), which have been FDA approved for the treatment of chronic myelogenous leukemia, HER2-positive breast cancer, non-small cell lung cancer, colorectal cancer, and gastrointestinal stromal and advanced kidney cancer, respectively. This evidence concerns the gene ERBB2 and breast cancer.