P16INK4A stained slides (n = 90) were scored on two separate aspects: the number of P16INK4A positive tumor cells present (0: <5%; 1: 5-25%; 2: 25-50%; 3: > 50%), and the intensity of p16INK4A staining (0 = absent; 1 = weak; 2 = moderate; 3 = strong). The gene discussed is CDKN2A; the disease is neoplasm.