Although many cases of language impairment are multifactorial, mutations in a single gene on 7q31, FOXP2, have been shown to cause developmental verbal dyspraxia in a large pedigree, called the KE family (Lai et al. 2000, 2001), and a number of individual cases [reviewed in Fisher and Scharff (2009)]. Here, FOXP2 is linked to childhood apraxia of speech.