Immunofluorescence in the EBV-positive NPC cell line C666-1 revealed that after LMP1 knockdown with siRNA at 50 nm or 100 nm, LMP1, p-mTOR and p-4EBP1 were significantly deregulated compared to the C666-1-NC-siRNA cell line (Figure 4). Here, EIF4EBP1 is linked to nasopharyngeal carcinoma.