LMP1 activate the PI3K/AKT/mTOR signaling pathway in B lymphocytes [21], and the mTOR signaling pathway has been identified as a downstream component of the PI3K/AKT pathway in the LMP2A-transfected NPC cell lines HONE1 and AD/AH [22]. The gene discussed is MTOR; the disease is nasopharyngeal carcinoma.