MBL2 and Autoimmunity: In addition, MBL has an important role in clearance of apoptotic cells (MBL is recruited from noncutaneous sources to bind apoptotic keratinocytes and induce their uptake by dendritic cells) [38], the accumulation of which can favor autoimmunity, as the release of intracellular components triggers inflammatory cytokine production and development of reactive clones, leading to autoantibody formation [39,40].