We did not detect hypermethylation of the BRCA1 promoter (Amplicons BRCA1_2 and BRCA1_3 in Figure 1A), which might be explained by the absence of the rare metaplastic subtype of basal-like breast cancers, to which most methylation events of BRCA1 seem to be restricted [26]. Here, BRCA1 is linked to breast cancer.