In this study, we also found that the level of apoB was higher in the CC genotype than the "T" allele carriers (CT+TT) in CAD combined with T2DM patients, indicating that PPARγC161→T reduces the risk of hyperlipidemia, and further diminishes the risk of severity of atherosclerotic vessels in patients with CAD and T2DM. This evidence concerns the gene APOB and type 2 diabetes mellitus.