KRT18 and metabolic dysfunction-associated steatohepatitis: Mallory-Denk bodies (MDBs), hepatic inclusion bodies observed in diverse chronic liver diseases such as alcoholic and non-alcoholic steatohepatitis, chronic cholestasis, metabolic disorders and hepatocellular neoplasms, are composed of aggregates of, in addition to other proteins, K18 and K8 in disproportional ratio that are hyperphosphorylated at multiple residues in both keratins, including Ser33 and Ser52 in the former, and Ser73 and Ser 341 in the latter [18-22].