HLA-DRB1 and malaria: However, conserved HABPs were found to be neither antigenic nor immunogenic or protection inducers when tested in Aotus monkeys, a non-human primate model highly susceptible to human malarias [8], [9] and whose immune system molecules share a high degree of similarity with their human counterparts, specially with those involved in antigen presentation such as α/β TCRs [10], [11] and MHCII–HLA-DRβ1*-like molecules (88% to 100% similarity is reported for the Peptide binding region or PBR of these molecules) [12].