When using Tukey-Kramer method to examine all pairwise differences between different stages, the expression levels of pTyr284-Ack1 and pTyr176-AKT in LNMM were significantly higher than those of all the earlier tumor stages; the expression levels were significantly lower in the normal samples when compared to those of all the later stages except for hyperplasia (Tables 2 and 3). Here, AKT1 is linked to neoplasm.