However, in the younger group, age ≤ 57 years old, individuals with AG or GG alleles of GSTP1 had a 2.18-fold risk (95% CI: 1.09-4.36, p = 0.02) and 5.64-fold risk (95% CI: 1.02-31.18, p = 0.04) of developing HCC compared to individuals with AA alleles, after adjustment for other confounders, but no association was found in the older group, aged > 57 years. The gene discussed is GSTP1; the disease is hepatocellular carcinoma.