High efficacy of a Listeria-based Recently, a recombinant strain of attenuated S. typhimurium expressing a gene encoding LIGHT, a cytokine known to promote tumor rejection has been reported to inhibit growth of primary tumors, as well as the dissemination of pulmonary metastases, in various mouse tumor models employing murine carcinoma cell lines in immunocompetent mice. This evidence concerns the gene TNFSF14 and neoplasm.