SLPI and endophthalmitis: Given what is known about the role of SLPI in other tissues such as lung, skin, and placenta [8, 13, 14] and our previous study of SLPI in a murine model of S. aureus endophthalmitis [10], our findings further support that SLPI is secreted in order to promote the early eradication of invading microorganisms and to protect the eye against proteolytic destruction by inflammatory cells.