IFN-γ did not induce significant MMP-1 nor did it induce significant MMP-3 production (mean ± SEM, ng/ml) in RA FLS over 72 hours (IFN-γ (10 ng/ml) versus control media at 72 hrs; MMP-1 = 15 ± 6 vs. 9.5 ± 3 and MMP-3 = 3.7 ± 1.7 vs. 3.1 vs. 1.4). Here, MMP1 is linked to rheumatoid arthritis.