Chen et al. report that Type I epithelial ovarian cancer (EOC) cells have high levels of IKKb expression due to low hsa-miR-199a; therefore, when stimulated, nuclear factor-kB (NF-kB) activation leads to cytokine production, cell proliferation and induction of antiapoptotic proteins. The gene discussed is NFKB1; the disease is ovarian carcinoma.