Soluble CD14 levels were significantly increased in serum of children with pneumonia (including patients with bacterial and non-bacterial pneumonia; median: 11433 ng/ml; range: 5429-15460 ng/ml) compared to CF (median: 4168; ng/ml; range: 2437-6061 ng/ml), asthma (median: 2960; ng/ml; range: 2134-5588 ng/ml) and control (median: 2654; ng/ml; range: 2154-3764 ng/ml) subjects with almost no overlap between pneumonia patients and the other patient groups (Figure 1). This evidence concerns the gene CD14 and cystic fibrosis.