Additionally, while a marked difference in the velocity of cells tracked within and outside of BCG induced granulomas showed that the granuloma per se was capable of inducing a change in cell movement [19], CD8+ T cells migrated without apparent constraint into, within and out of L. donovani granulomas, and non-antigen specific cells showed the same speed of cell movement whether located inside or outside of granulomas. This evidence concerns the gene CD8A and Granuloma.