Without distinction between trpm1-L or trpm1-S, trpm1 has been reported to be detected in human primary melanocytes [13], poorly metastatic melanoma cell lines [14,15], mouse retinal pigment epithelium (RPE) [16], and subsets of ON and hyperpolarization of neuron by light (OFF) BCs [17,18]. The gene discussed is TRPM1; the disease is melanoma.