ROM1 and retinitis pigmentosa 1: Two amino acid substitutions (p.Pro60Thr and p.Thr108Met) in a single allele of ROM1 in an autosomal dominant RP patient and three different single amino acid substitutions (p.Gly75Asp, p.Leu114fs, p.Arg242Glu) in patients with sporadic RP have been reported [41-43].