In Asian Indians, studies have investigated the allele frequencies with ranges 0.031-0.094 for ε2; 0.803-0.968 for ε3 and 0.000-0.133 for ε4.[19] Frequency of apoE ε3 allele was found to be high (0.913) in people of north India.[17] In another study on Asian Indians, individuals with at least a ε4 allele were considered at risk to develop premature Myocardial Infarction (MI), independent of other risk conventional risk factors.[20] Most of these studies are either from the north, west, central, and southern part of India.[15, 7–32] Studies from eastern part of India are lacking. This evidence concerns the gene APOE and myocardial infarction.