Hemophilia A (HA) is a common inherited recessive X-linked disorder of blood clotting caused by deficiency of factor VIII in the coagulation cascade and affects approximately 1 in 5,000 males world-wide.[1, 2] The FVIII gene, comprises 26 exons ranging from 69 bp (exon 5) to 3.1 kb (exon 14) in size, spans 186 kb of genomic DNA and produces a 9030 nt mRNA. The gene discussed is F8; the disease is hemophilia A.