p27, Skp2, Cox2, CycD1 and Ki67 are considered as tumour and/or proliferation markers (Huang et al, 2003; Siggelkow et al, 2004; Adjei, 2005; Vig-Varga et al, 2006; Garg et al, 2008; Park et al, 2008; Chang et al, 2009; Meeran et al, 2009; Mukhopadhyay et al, 2009), ImAnOx and carbonyls are oxidative markers (Nyström, 2005; Bahar et al, 2007) and MMP-9, -3 and -2 are MMPs that are expressed in various pathological processes such as inflammation and cancer and also in response to infections (Korpos et al, 2009; Oikonomidi et al, 2009; Vanlaere and Libert, 2009). This evidence concerns the gene SKP2 and cancer.