Cyclin E1, epithelial growth factor (EGF) [37], IL-6, CXCL8, IL-10, and IL-1RA have all been shown to be elevated in individuals with pancreatic cancer [43,44] and high IL-6 or IL-10 levels correlated to poor survival [43]. The gene discussed is CCNE1; the disease is familial pancreatic carcinoma.