These studies have described up-regulation of MN1[74], NME1[75], HOXA10[59], and FLT3[76] in poor prognosis AML which correlates with our comparison, while there are conflicting reports of HOXA4[59], [60] and CD34 gene expression in poor prognosis AML. The gene discussed is FLT3; the disease is acute myeloid leukemia.