TBXAS1 is an enzyme that converts prostaglandin H2 into thromboxane A2.[90] Thromboxane A2 induces platelet aggregation, smooth muscle contraction, and possibly modulates mitogenesis and apoptosis.[91] Although there have been no previous reports describing TBXAS1 expression in AML, our comparison included three papers that associated increased expression of TBXAS1 with a poor prognosis. This evidence concerns the gene TBXAS1 and acute myeloid leukemia.