Although most of these genes have been associated with AML elsewhere in the literature, several genes (VCAN and PGDS) have only been described in AML cell lines and a surprising number of the genes (HLA-DPA1, ITM2A, RBPMS, RGS10, RNASE2 and TRH) have not been specifically described in AML. The gene discussed is RBPMS; the disease is acute myeloid leukemia.